FAQs
If you’ve wondered how long your probiotics last after being opened, whether you can take them while pregnant, or if there’s added dairy, you’ve come to the right place. Find an answer for these questions, and more, below.
For information on storage and handling of probiotics, refer to our information sheet
Pharmacovigilance: If you’d like to report a suspected adverse event or product complaint related to an Evolution Health product, please contact us.
What is a microbiome and why is it important?
The human microbiome is a term used to describe the large communities of microbes that coat the human body, inside and out. Invisible to the human eye, this extraordinary ecosystem is made up of a diverse collection of bacteria, fungi, viruses and parasites, that is as unique to you as your fingerprint. When in balance, the microbiome coexists peacefully with your body, supporting health like a functioning organ. Changes to this balance can affect your general health and wellbeing.
What is a probiotic?
The definition of a probiotic is a live microorganism that can offer health benefits to the host (that’s you) when taken in adequate amounts.[1] Beneficial microbes can be found in fermented foods such as yoghurt and kimchi.[2] By supplementing with probiotics, you can choose the type and strength of probiotic specific to your health needs. For a supplement to be called a ‘probiotic’ in Australia, it should contain live bacteria. [3]
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[1] Sanders ME. How do we know when something called “probiotic” is really a probiotic? A guideline for consumers and health care professionals. Functional Food Reviews. 2009;1(1):3-12.
[2] Marco ML, Heeney D,
Binda S, Cifelli CJ, Cotter PD, Foligné B, Gänzle M, Kort R, Pasin G, Pihlanto
A, Smid EJ. Health benefits of fermented foods: microbiota and beyond. Current opinion in biotechnology. 2017 Apr 1;44:94-102.
[3] Australian Government Department of Health. Therapeutic Goods Association. Australian Regulatory Guidelines for Advertising Therapeutic Goods (ARGATG). Advertising Interface Products. Australain Government. [Updated October 2020, Cited 17/3/22].https://www.tga.gov.au/book-page/advertising-interface-products
What does a probiotic do?
Probiotics are beneficial bacteria that support our health and wellbeing. Even though probiotic supplements are taken by mouth, once they reach the gut these clever little microbes can send messages to distant organs to influence health and function.[3] Some of the many systems that benefit from probiotics include:
· Digestive system
· Immune system
· Skin
· Brain
· Urinary system[4]
And much more
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[3] Australian Government Department of Health.Therapeutic Goods Association.Australian Regulatory Guidelines for Advertising Therapeutic Goods (ARGATG).Advertising Interface Products.Australain Government. [Updated October 2020, Cited 17/3/22]. https://www.tga.gov.au/book-page/advertising-interface-products
[4] Ahlawat S, Sharma KK. Gut–organ axis: a microbial outreach and networking. Letters in applied microbiology. 2021 Jun;72(6):636-68.
How do probiotics work?
Probiotics are multi-talented. Various strains of probiotics have different actions which allow them to support our health in many different ways[5]. Some of these include:
· Supporting the intestinal microbiome – helping to improve the balance between ‘good’ and ‘bad’ bacteria
· Supporting gastrointestinal mucosal membrane health (AKA gut barrier) – Part of your first line of defence for your precious immune system
· Supporting immune system health
· Supporting healthy bowel function and digestive system health – so that you can have a healthy relationship with the loo! [6],[7]
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[5] McFarlandLV, Evans CT, Goldstein EJ. Strain-specificity and disease-specificity of probiotic efficacy: a systematic review and meta-analysis. Frontiers in medicine. 2018 May 7;5:124.
[6] Devika Das J, Akhila
VS, Paul M, Shankar A, Joseph I, Thomas S. Modern Perspectives in Controlling Human Diseases through Probiotic Intervention. InHuman Microbiome 2022 (pp. 169-192). Springer, Singapore.
[7] Bhushan B, Singh BP, Saini K, Kumari M, Tomar SK, Mishra V. Role of microbes, metabolites and effector compounds in host–microbiota interaction: a pharmacological outlook. Environmental Chemistry Letters. 2019 Dec;17(4):1801-20.
What is a CFU?
CFU stands for ‘Colony Forming Unit’ – a term used to describe the measurement of live bacteria found in a probiotic supplement. Why is this important? Knowing the CFU count of your probiotic supplement helps you to identify the strength of the probiotic supplement, which plays an important role in determining the health benefits.[8]
Therefore, to help support positive health outcomes, Life-Space probiotics not only guarantee that you will receive the amount of CFU’s shown on the label, but we also offer a range of products with varying CFU counts to suit individual needs.
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[8] Gogineni VK, Morrow LE, Malesker MA. Probiotics: mechanisms of action and clinical applications. J Prob Health. 2013;1(1):1-1.
What is a probiotic strain and why is it important?
Just like you belong a country, state, town and your own home, probiotic bacteria belong to a genus, species, subspecies and finally, a strain. Not all probiotics are created equal and research has shown that certain health benefits of probiotics are associated with their specific strain.[9],[10] Check out the Life-Space probiotic supplement labels to find the strain names included in our formulas.
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[9] McFarland LV, Evans CT, Goldstein EJ. Strain-specificity and disease-specificity of probiotic efficacy: a systematic review and meta-analysis. Frontiers in medicine. 201 May 7;5:124.
[10] National Institute of Health: Office of Dietary Supplements. Probiotics: Fact Sheets for Health Professionals. US. National Institute of Health. [Updated December 2021, Cited 28 February 2022]. https://ods.od.nih.gov/factsheets/Pr biotics-HealthProfessional/
How often should I take probiotics?
The health benefits of probiotics are experienced during the time period they are supplemented.[11],[12] Therefore, it is recommended to take probiotics daily.[8]
Always read the label for further information and consult with your health care professional if you have questions
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[8]Gogineni VK, Morrow LE, Malesker MA. Probiotics: mechanisms of action and clinical applications. J Prob Health. 2013;1(1):1-1.
[11] Monteagudo-Mera A, Rastall RA, Gibson GR, Charalampopoulos D, Chatzifragkou A. Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health. Applied microbiology and biotechnology. 201 Aug;103(16):6463-72.
[12] Ciorba MA. A gastroenterologist's guide to probiotics. Clinical gastroenterology and hepatology. 2012 Sep 1;10(9):960-8.
When is the best time to take a probiotic?
Probiotics can be taken at any time of day but some evidence suggests they are best taken before or during a meal.[13] If you are also taking antibiotics, it is recommended to take at least 2 hours away from probiotics.[13]
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[13] Health Canada. Drug and Health Products: Probiotics. Canada 2021. [Cited November 11 2021]. Available from http://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq.do?atid=probio&lang=eng
How long does it take for probiotics to work?
A recent research paper showed that when using probiotics for certain gut imbalances, positive results were shown from as early as 1-2 weeks. The same study showed that a treatment period of 9-240 weeks was more effective than a treatment period of 3-4 weeks.[14]
However, it is important to remember that everyone’s body and health needs are different and therefore, for more specific advice, please speak to your health professional.
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[14] Ritchie ML, Romanuk TN. A meta-analysis of probiotic efficacy for gastrointestinal diseases. PloS one. 2012 Apr 18;7(4):e34938.
What is the history of probiotic use?
Probiotics are typically derived from species with a long history of use, whether they have been used in foods or are naturally occurring in the human microbiome. [4] The most commonly used probiotic species and strains are generally used in healthy individuals and can provide many health benefits when used according to the directions.[4],[15] Those with severe illness should seek advice from their health practitioner before taking probiotic supplements.[3]
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[3] Australian Government Department of Health.Therapeutic Goods Association.Australian Regulatory Guidelines for Advertising Therapeutic Goods (ARGATG).Advertising Interface Products.Australain Government. [Updated October 2020, Cited 17/3/22]. https://www.tga.gov.au/book-page/advertising-interface-products
[4] Ahlawat S, Sharma KK. Gut–organ axis: a microbial outreach and networking. Letters in applied microbiology. 2021 Jun;72(6):636-68.
[15] Martin CM, Bryan G. Demystifying Probiotics: Use in the Elderly. The Consultant Pharmacist®. 201 Aug 1;32(8):434-40.
Can I take probiotics during pregnancy?
Research has shown that probiotics can be used during pregnancy and have shown benefits during pregnancy.[16] For more specific advice, please consult your health practitioner.
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[16] Elias J, Bozzo P, Einarson A. Are probiotics safe for use during pregnancy and lactation?. Canadian Family Physician. 2011 Mar 1;57(3):299-301.
What is the difference between prebiotic and probiotic?
Nothing goes to waste in our microbial ecosystem. Certain foods that we can’t digest become the food for our beneficial bugs - these foods are called ‘prebiotics’. Prebiotics can be found in fibrous foods, such as fruit and wholegrains, as well as foods that contain flavanols such as green tea and grape seed. [17]
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[17]Davani-Davari D, Negahdaripour M, Karimzadeh I, Seifan M, Mohkam M, Masoumi SJ, Berenjian A, Ghasemi Y. Prebiotics: definition, types, sources, mechanisms, and clinical applications. Foods. 2019 Mar;8(3):92.
Which age groups can benefit from probiotics?
As we evolve with age, so does our microbiome. Taking care of your microbiome throughout your lifespan can play a key role in supporting health and longevity and the best part is, it’s never too late to start. Each age group presents with different health needs and challenges, from establishing a healthy microbiome at birth, to restoring and maintaining a healthy microbiome during our adult and senior years. [18] , [8] Different probiotic strains cater to the needs of different age groups and therefore it is important to choose the right probiotic to suit your individual needs.
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[8] Gogineni VK, Morrow LE, Malesker MA. Probiotics: mechanisms of action and clinical applications. J Prob Health. 2013;1(1):1-1.
[18] Robertson RC, Manges AR, Finlay BB, Prendergast AJ. The human microbiome and child growth–first 100 days and beyond. Trends in Microbiology. 2019 Feb 1;27(2):11-47.
How do probiotics support immune health?
Up to 70% of the immune system is located in your gut.[19] Just like neighbours, the gut microbiome and immune system live alongside each other and communicate regularly. If the gut microbiome is in balance, this forms a positive relationship which supports the health and function of our body.[12]
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[12] Ciorba MA. A gastroenterologist's guide to probiotics. Clinical gastroenterology and hepatology. 2012 Sep 1;10(9):960-8.
[19] Vighi G, Marcucci F, Sensi L, Di Cara G, Frati F. Allergy and the gastrointestinal system. Clin Exp Immunol. 2008 Sep;153 Suppl 1(Suppl 1):3-6. doi: 10.1111/j.136 2249.2008.03713.x. PMID: 18721321; PMCID: PMC2515351.
Why is the gut sometimes called our second brain?
The microbiome-gut-brain axis describes a complex web that connects parts of the nervous system with the gut and the microbes that grow within it. This connection allows gut health to influence brain health and vice versa. If you have ever had the feeling of butterflies in your tummy, than you have experienced this connection first-hand.[20]
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[20] Vighi G, Marcucci F, Sensi L, Di Cara G, Frati F. Allergy and the gastrointestinal system. Clinical & Experimental Immunology. 200 Sep;153(Supplement_1):3-6
What is the skin microbiome?
The skin microbiome is like our very own invisible ecosystem that inhabits every square centimeter of our skin. It is made up of a diverse mix of microbes, and can include anything from bacteria, viruses, fungi and even mites! Each of these microbes have their own unique and important role to play in the way that our skin functions. When these microbes live in balanced and diverse communities, they support our skin function and live in harmony with our skin. Alternatively, when there are imbalances within the microbial communities, this can pave the way for what is known as dysbiosis, and also dysbiosis-related skin conditions, such as acne.[21]
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[21] Dréno B, Dagnelie MA, Khammari A, Corvec S. The skin microbiome: a new actor in inflammatory acne. American Journal of Clinical Dermatology. 2020 Sep;21(1):18-24.
How can beneficial bacteria help with vaginal health?
Naturally occurring Lactobacilli bacteria, including L.crispatus and L. gasseri, play an important role in maintaining the health of your vagina [22] Lactobacilli are known for their ability to produce a substance known as lactic acid, an important substance which helps support a healthy vaginal microbiome. Whilst the thought of an acidic vaginal environment conjures up images of intense discomfort, it is generally considered a good thing, playing a protective role by keeping less vagina-friendly species of bacteria at bay.[23] An abundance of Lactobacilli bacteria is considered a sign of a healthy vaginal microbiome in the majority of women.[24]
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[22]Nader‐Macías ME, De Gregorio PR, Silva JA. Probiotic lactobacilli in formulas and hygiene products for the health of the urogenital tract. Pharmacology Research & Perspectives. 202 Oct;9(5):e00787
[23] Nunn KL, Forney LJ. Focus: microbiome: unraveling the dynamics of the human vaginal microbiome. The Yale journal of biology and medicine. 2016 Sep;89(3):331.
[24] Wissel E, Dunn A, Dunlop A. A Narrative Review on Factors Shaping the Vaginal Microbiome: Role of Health Behaviors, Clinical Treatments, and Social Factors. Authorea Preprints. 2020 Oct 5.
How can probiotics help with symptoms of medically diagnosed IBS?
Recent studies suggest that supplementing with beneficial probiotic bacteria can help relieve symptoms of MD-IBS. For instance, Lactobacillus plantarum 299v is a probiotic strain that attaches to the gut lining of the bowel and can relieve abdominal pain, bloating and gas, in addition to supporting healthy bowel function.[25]
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[25] Ducrotté P, Sawant P, Jayanthi V. Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome. World journal of gastroenterology: WJG. 2012 Aug 14;18(30):4012.
What does the gut microbiome have to do with cholesterol?
Whilst the digestive and cardiovascular systems are 2 very different systems with very different jobs, they are connected via what has been referred to as the ‘gut-heart axis’. [4] Taking care of your gut microbiome may not only help maintain healthy cholesterol in healthy individuals, but can also support healthy function of the cardiovascular system. Probiotic bacteria, including those belonging to the genera Lactobacillus and Bifido acterium, can help maintain healthy cholesterol in healthy people.[26]
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[4] Ahlawat S, Sharma KK. Gut–organ axis: a microbial outreach and networking. Letters in applied microbiology. 2021 Jun;72(6):636-68.
[26]Kriaa A, Bourgin M, Mkaouar H, Jablaoui A, Akermi N, Soussou S, Maguin E, Rhimi M. Microbial reduction of cholesterol to coprostanol: an old concept and new insights. Catalysts. 201 Feb;9(2):167
Do Life-Space Probiotics need to be refrigerated?
In order to provide live, beneficial bacteria, a probiotic supplement should use bacterial strains that can survive the harsh environment of processing and storage.[27]
This is why your probiotic choice matters.
Life-Space probiotic formulas are developed using a tried and tested technology known as ‘freeze drying’, which produces probiotics that are live, stable and functional, including at room temperature (below 30˚ C) [28] We are proud to offer the convenience of shelf stable probiotic products using this very technology!
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[28] Fonseca F, Cenard S, Passot S. Freeze-drying of lactic acid bacteria. In Cryopreservation and freeze drying protocols 2015 (pp. 477-488). Springer, New York, NY.
What are the small blue canisters in your product for? How do I dispose of these responsibly?
The blue canister is a desiccant. The purpose of a desiccant is to attract moisture and help preserve the probiotic formulation. Moisture can be damaging to probiotic bacteria and therefore we recommend keeping these cannisters in the container with your probiotics for the duration of use. Once the probiotics have been consumed, you can dispose of the cannisters with your general waste.
How can I responsibly dispose of my Life-Space Container?
At Life-Space we believe maintaining the health of the planet as much as we believe in maintaining your health. Please see below details on how to dispose of your container responsibly.
· Your probiotic capsule container is made from glass, which can be responsibly disposed of in your recycling bin.
· The plastic label covering the glass jar can removed and recycled at your local participating Red Cycle Supermarket https://redcycle.net.au/where-to-redcycle/
· Please remove the blue cannisters and jar lid prior to recycling. These can be disposed of in your general waste.
If you would like to learn more about the microbiome or the Life-Space probiotic range, please feel free to send your questions through to our team.
Email – info@life-spacegroup.com.au
Phone – 03 9828 9400